Tailored transplants aim to beat inherited blood cancers

NCT ID NCT07524530

First seen Apr 18, 2026 · Last updated Apr 29, 2026 · Updated 2 times

Summary

This study tests a stem cell transplant approach for people whose blood cancer is caused by an inherited RUNX1 gene mutation. Researchers will adjust chemotherapy and supportive care doses for each patient to see if this improves survival compared to past results. About 98 participants aged 4 to 70 with leukemia or related cancers will receive a half-matched donor transplant and be followed for 3 years.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.