Stem cell patch aims to mend broken hearts in landmark trial

NCT ID NCT07471698

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial tests whether a patch loaded with lab-grown heart muscle cells can help repair damaged heart tissue. Sixteen people with severe heart failure who are already scheduled for bypass surgery will receive either the stem cell patch or a blank patch during their operation. The main goals are to check safety and see if the patch improves heart function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

human induced pluripotent stem cell-derived cardiomyocytes (HiCM-188) loaded onto a chitosan patch

What this could lead to

If it works, this could point toward a way to repair damaged heart muscle and improve heart function in people with severe heart failure.

What could go wrong

This is a very early, small study (16 people) focused on safety. The stem cell patch may not improve heart function, and there are risks like abnormal heart rhythms or tumor formation.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

heart failure myocardial ischemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Second Xiangya Hospital of Central South University

    Changsha, China

    Contact

    Contact