Could your own bone marrow repair a failing heart?
NCT ID NCT06258447
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a patient's own bone marrow cells, processed and delivered to the heart via a catheter, can improve outcomes for people with chronic ischemic heart failure. About 250 participants with moderate-to-severe heart failure will either receive the cell treatment or a sham procedure. The goal is to see if the treatment reduces deaths, hospitalizations, and improves quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
patient's own bone marrow cells (autologous bone marrow mononuclear cells)
What this could lead to
If it works, this could offer a new way to improve heart function and reduce hospitalizations for people with chronic heart failure.
What could go wrong
This is a mid-stage trial with 250 participants, so results are not yet proven. The procedure involves bone marrow aspiration and heart catheterization, which carry risks like bleeding or infection.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cleveland Clinic
WITHDRAWNCleveland, Ohio, 44195, United States
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Emory University
RECRUITINGAtlanta, Georgia, 30322, United States
Contact Email: •••••@•••••
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Henry Ford Hospital
RECRUITINGDetroit, Michigan, 48202, United States
Contact Email: •••••@•••••
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Morton Plant Hospital - BayCare
RECRUITINGClearwater, Florida, 33756, United States
Contact Email: •••••@•••••
Contact
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University of Wisconsin-Division of Cardiovascular Medicine
RECRUITINGMadison, Wisconsin, 53792, United States
Contact Email: •••••@•••••