Could your own bone marrow repair a failing heart?

NCT ID NCT06258447

Recruiting now Disease control Sponsor: BioCardia, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a patient's own bone marrow cells, processed and delivered to the heart via a catheter, can improve outcomes for people with chronic ischemic heart failure. About 250 participants with moderate-to-severe heart failure will either receive the cell treatment or a sham procedure. The goal is to see if the treatment reduces deaths, hospitalizations, and improves quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: patient's own bone marrow cells (autologous bone marrow mononuclear cells)
What this could lead to: If it works, this could offer a new way to improve heart function and reduce hospitalizations for people with chronic heart failure.
What could go wrong: This is a mid-stage trial with 250 participants, so results are not yet proven. The procedure involves bone marrow aspiration and heart catheterization, which carry risks like bleeding or infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ISCHEMIC HEART FAILURE

Contacts and locations

Locations

Cleveland Clinic
WITHDRAWN

Cleveland, Ohio, 44195, United States
Emory University
RECRUITING

Atlanta, Georgia, 30322, United States
Henry Ford Hospital
RECRUITING

Detroit, Michigan, 48202, United States
Morton Plant Hospital - BayCare
RECRUITING

Clearwater, Florida, 33756, United States
University of Wisconsin-Division of Cardiovascular Medicine
RECRUITING

Madison, Wisconsin, 53792, United States

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