Could a common diuretic protect hearts in rare ARVD?
NCT ID NCT03593317
First seen Feb 24, 2026 · Last updated May 15, 2026 · Updated 12 times
Summary
This study tests whether spironolactone, a medication that helps the body get rid of extra fluid, can slow down heart muscle damage and reduce dangerous heart rhythms in people with arrhythmogenic right ventricular dysplasia (ARVD). ARVD is a rare condition where heart muscle is replaced by fat and scar tissue, leading to electrical problems. About 120 adults with ARVD will be randomly assigned to take either spironolactone or a placebo for up to 3 years. Researchers will measure changes in heart function and rhythm to see if the drug helps preserve heart health and improve quality of life.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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CHU Amiens Picardie
NOT_YET_RECRUITINGAmiens, France
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CHU Dijon
RECRUITINGDijon, France
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Groupe Hospitalo Universitaire Caremeau
NOT_YET_RECRUITINGNîmes, France
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Hôpital Arnaud de Villeneuve
RECRUITINGMontpellier, France
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Hôpital Cardiologique Louis Pradel
RECRUITINGBron, France
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Hôpital Gabriel Montpied
NOT_YET_RECRUITINGClermont-Ferrand, France
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Hôpital Laennec
RECRUITINGNantes, France
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Hôpital Michallon
NOT_YET_RECRUITINGGrenoble, France
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Hôpital Pitié Salpetrière
RECRUITINGParis, France
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Hôpital Rangueil
NOT_YET_RECRUITINGToulouse, France
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Hôpital de Haut-Lévêque
NOT_YET_RECRUITINGPessac, France
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Hôpital de la Timone
NOT_YET_RECRUITINGMarseille, France
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Nouvel Hôpital Civil
NOT_YET_RECRUITINGStrasbourg, France
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