New device aims to zap away atrial fibrillation

NCT ID NCT05115214

Recruiting now Disease control Sponsor: Medtronic Cardiac Ablation Solutions Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new catheter system called SpherePVI that uses heat to destroy tiny areas of heart tissue causing atrial fibrillation (an irregular heartbeat). About 150 people with symptomatic atrial fibrillation will undergo the procedure. The goal is to see if the device can safely and effectively restore a normal heart rhythm.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: SpherePVI™ catheter (a device that uses heat energy to destroy small areas of heart tissue causing irregular heartbeat)
What this could lead to: If successful, this could provide a safer, more effective way to treat atrial fibrillation and help patients maintain a normal heart rhythm without long-term medication.
What could go wrong: This is an early-stage study with only 150 participants, so results may not apply to everyone. There are risks like stroke, heart damage, or bleeding from the procedure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation paroxysmal atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIAL FIBRILLATION

Contacts and locations

Locations

Homolka Hospital
RECRUITING

Prague, Czechia
Institute Klinicke a Experimentalni Mediciny
RECRUITING

Prague, Czechia

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