No more tubes? swallowable capsule could revolutionize stomach acid testing
NCT ID NCT00702533
First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 2 times
Summary
This study tests a new, less invasive way to measure stomach acid using a small wireless capsule (SmartPill) that patients swallow. It compares the capsule's accuracy to the standard method, which involves a tube placed through the nose into the stomach. The study includes healthy volunteers and people with acid-related disorders like Zollinger-Ellison syndrome and GERD.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
SmartPill (wireless capsule) and Pentagastrin injection
What this could lead to
If successful, this could replace the uncomfortable nasogastric tube test for measuring stomach acid, making diagnosis simpler and more tolerable for patients.
What could go wrong
This is an early-stage study with only 80 participants. The capsule may not be as accurate as the standard method, and results may not apply to all acid-related conditions.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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National Institutes of Health Clinical Center
Bethesda, Maryland, 20892, United States