Crohn's blockage showdown: drugs or surgery for better quality of life?
NCT ID NCT05584228
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial compares two approaches for people with Crohn's disease who have a narrowed section of the small bowel causing symptoms. One group receives a combination of two drugs (azathioprine and infliximab), while the other group undergoes surgery to remove the narrowed segment. The goal is to see which treatment leads to a better quality of life over time.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- azathioprine and infliximab
- What this could lead to
- If one approach proves better, it could guide treatment decisions for people with Crohn's disease who have bowel blockages.
- What could go wrong
- This is a mid-sized trial, and results may not apply to all Crohn's patients. Both treatments have risks, including infection or surgical complications.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CHU de Nantes
Nantes, 44093, France
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