Crohn's blockage showdown: drugs or surgery for better quality of life?

NCT ID NCT05584228

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial compares two approaches for people with Crohn's disease who have a narrowed section of the small bowel causing symptoms. One group receives a combination of two drugs (azathioprine and infliximab), while the other group undergoes surgery to remove the narrowed segment. The goal is to see which treatment leads to a better quality of life over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

azathioprine and infliximab

What this could lead to

If one approach proves better, it could guide treatment decisions for people with Crohn's disease who have bowel blockages.

What could go wrong

This is a mid-sized trial, and results may not apply to all Crohn's patients. Both treatments have risks, including infection or surgical complications.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CROHN DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Constriction, Pathologic Crohn disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU de Nantes

    Nantes, 44093, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••