New study aims to perfect dosing of Parkinson's rescue drug
NCT ID NCT07145190
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing SL-APO (Kynmobi), a fast-acting film placed under the tongue, to treat OFF episodes in people with Parkinson's disease. OFF episodes are times when Parkinson's symptoms return between medication doses. The study will enroll 90 adults and observe how doctors adjust the dose in real-world settings, aiming to find the most effective and safe dose for each person. The goal is to improve patient satisfaction and treatment success.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
SL-APO (apomorphine sublingual film, brand name Kynmobi)
What this could lead to
If successful, this study could help doctors find the most effective and tolerable dose of SL-APO for quickly relieving Parkinson's OFF episodes, improving patient satisfaction and daily function.
What could go wrong
This is an early real-world study with only 90 participants, not a large controlled trial. Results may not apply to all patients, and side effects like nausea or dizziness are possible.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Alexianer St. Joseph Berlin-Weißensee GmbH
NOT_YET_RECRUITINGBerlin, 13088, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Charité - Universitätsmedizin Berlin - Sektion für Bewegungsstörungen und Neuromodulation
RECRUITINGBerlin, 10117, Germany
Contact Email: •••••@•••••
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Die Nerven Docs
RECRUITINGSiegen, 57072, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Katholisches Klinikum Bochum gGmbH, Universitätsklinikum St.Josef-Hospital, Klinik für Neurologie
NOT_YET_RECRUITINGBochum, 44791, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Klinik am Tharandter Wald
RECRUITINGHetzdorf, 09633, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Klinik für Neurologie und Neurologische Frührehabilitation
NOT_YET_RECRUITINGOsnabrück, 49076, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Neurologie am Funkerberg
RECRUITINGWusterhausen, 15711, Germany
Contact Phone: •••-•••-••••
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Neurologische Klinik Sorpesee
RECRUITINGSundern, 59846, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Praxis für Neurologie
RECRUITINGBerlin, 15366, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Praxis für Neurologie und Geriatrie
RECRUITINGUlm, 89073, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Praxis für Neurologie und Psychiatrie
RECRUITINGFulda, 36037, Germany
Contact Email: •••••@•••••
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UNIVERSITÄTSKLINIKUM FREIBURG - Neurozentrum Klinik für Neurologie und Neurophysiologie im Neurozentrum
NOT_YET_RECRUITINGFreiburg im Breisgau, D-79106, Germany
Contact Phone: •••-•••-••••