Immunotherapy cocktail takes on tough pancreatic cancer

NCT ID NCT06050317

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial is testing whether adding the immunotherapy drug sintilimab to chemotherapy and radiation can help people with inoperable pancreatic cancer live longer. The study will enroll 25 participants who have not had prior treatment. Researchers will track how long the cancer stays under control and any side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Sintilimab (an immunotherapy drug) plus chemotherapy (mFFN or NALIRIFOX) and radiation

What this could lead to

If it works, this could offer a new treatment option to control inoperable pancreatic cancer and extend survival.

What could go wrong

This is a small, early-phase trial with only 25 people, so results may not apply widely. Side effects from the combination therapy could be significant.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

malignant pancreatic neoplasm pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Radiation Oncology, Shandong Cancer Hospital and Institute

    RECRUITING

    Jinan, Shandong, 0531, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••