Computer-Guided statin dosing shows promise for liver patients

NCT ID NCT07459972

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a computer program could help doctors choose the right dose of simvastatin for people with cirrhosis and high blood pressure in the liver. Twenty-two patients received either 5 mg or 15 mg of simvastatin daily for three months. Researchers measured changes in liver blood flow and checked for side effects to see if the computer-guided dosing was safe and effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Simvastatin

What this could lead to

If successful, this approach could help doctors personalize statin doses for people with liver disease, potentially reducing complications from high blood pressure in the liver.

What could go wrong

This was a small pilot study with only 22 participants, so results may not apply to everyone. The study focused on short-term safety and blood flow changes, not long-term outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver portal hypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Kafrelsheikh University

    Cairo, Egypt