New cancer drug SIM0610 enters first human tests
NCT ID NCT07348211
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase trial is testing an experimental drug called SIM0610 in 260 adults with advanced solid tumors, including lung, colorectal, head and neck, and liver cancers. The main goals are to check the drug's safety, find the right dose, and see if it shrinks tumors. Participants receive the drug through an IV infusion.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- SIM0610 (an experimental drug given by intravenous infusion)
- What this could lead to
- If successful, this could point toward a new treatment option for several advanced solid tumors.
- What could go wrong
- This is a very early Phase 1 trial, so the drug may not be safe or effective. It is the first time SIM0610 is tested in humans, and many early-stage drugs never advance.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Chongqing Cancer Hospital
NOT_YET_RECRUITINGChongqing, Chongqing Municipality, 400000, China
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Harbin Medical University Cancer Hospital
NOT_YET_RECRUITINGHarbin, Heilongjiang, 150000, China
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Shanghai East Hospital
NOT_YET_RECRUITINGShanghai, Shanghai Municipality, 200000, China
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Shanghai Pulmonary Hospital
NOT_YET_RECRUITINGShanghai, Shanghai Municipality, 200000, China
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The Affiliated Cancer Hospital of Shandong First Medical University& Shan Dong Cancer Hospital
RECRUITINGJinan, Shandong, 250117, China
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Zhongshan Hospital, Fudan University
NOT_YET_RECRUITINGShanghai, Shanghai Municipality, 200000, China
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the First Hospital of China Medical University
NOT_YET_RECRUITINGShenyang, Liaoning, 110000, China
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