Jiangsu Simcere Pharmaceutical Co., Ltd.

This early-stage study tests a new drug called SIM0610 in about 260 adults with advanced solid tumors (e.g., lung, colorectal, head and neck, liver cancer) that have spread. The main goals are to check the drug's safety and find the right dose, while also looking for signs that i…

This study tests whether adding the experimental drug suvemcitug to standard chemotherapy (FTD/TPI) helps people with advanced colorectal cancer that has stopped responding to other treatments live longer. About 464 participants will receive either the combination or a placebo pl…

This study tests whether a new drug called SIM0270, combined with everolimus, can slow down or stop the growth of a certain type of advanced breast cancer (ER+/HER2-) that has already been treated with CDK4/6 inhibitors. About 460 participants will receive either the experimental…

This early-phase trial tests a new drug called SIM0500 in about 130 adults with multiple myeloma that has come back or stopped responding to standard treatments. The drug is designed to help the immune system attack cancer cells from three different angles. The main goal is to ch…

This early-stage study tests a new drug, SIM0609, in 232 adults with advanced solid tumors that have not responded to standard treatments. The main goals are to check the drug's safety and find the right dose, while also watching for any signs that it might shrink tumors. This is…

This early-stage trial in 60 healthy Chinese adults checks how the body processes a new drug (SIM0270) when taken with other medicines like itraconazole, rifampin, or midazolam. The goal is to measure drug levels in the blood, not to treat any disease. Participants must be health…