Jiangsu Simcere Pharmaceutical Co., Ltd.

This early-stage trial tests a new drug called SIM0500 in 130 adults with multiple myeloma that has returned or stopped responding to treatment. SIM0500 is a tri-specific antibody designed to help the immune system attack cancer cells. The study will first find the safest dose, t…

This early-stage trial tests a new drug called SIM0613 in about 294 adults with advanced solid tumors that have worsened after standard treatments. The study has two parts: first, finding a safe dose, then expanding to see if the drug shrinks tumors. The main goals are safety and…

This early-phase trial is testing an experimental drug called SIM0610 in 260 adults with advanced solid tumors, including lung, colorectal, head and neck, and liver cancers. The main goals are to check the drug's safety, find the right dose, and see if it shrinks tumors. Particip…

This phase 3 trial is testing whether adding the experimental drug suvemcitug to standard chemotherapy (trifluridine/tipiracil) helps people with metastatic colorectal cancer that no longer responds to other treatments live longer. About 464 participants will receive either the c…

This early-phase study tests a new drug called SIM0609 in adults with advanced solid tumors that have not responded to standard treatments. The main goals are to check the drug's safety, find the right dose, and see if it can shrink tumors. About 232 participants will take part a…

This early-stage study is testing a new drug, SIM0811, in 72 healthy Chinese adults to see if it is safe and how the body processes it. Participants receive a single dose of the drug or a placebo, and researchers monitor side effects and measure drug levels in the blood. The goal…

This early-stage study looks at how three common drugs (itraconazole, rifampin, and midazolam) affect the levels of an experimental drug called SIM0270 in the body. About 60 healthy Chinese adults aged 18 to 55 will take part. The goal is to gather safety and drug interaction inf…