Could viagra help COPD patients catch their breath?

NCT ID NCT05061368

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether sildenafil, a drug that widens blood vessels in the lungs, can improve exercise ability and reduce shortness of breath in people with mild COPD. Researchers think poor blood flow in the lungs may cause breathing trouble during activity. The trial will compare sildenafil to a placebo in 160 participants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Sildenafil (oral drug, a pulmonary vasodilator)

What this could lead to

If it works, this could offer a new way to help people with mild COPD breathe easier during exercise and be more active.

What could go wrong

This is an early phase 2 trial with only 160 participants. Sildenafil may not improve symptoms or could cause side effects like headache or flushing. Results may not apply to all COPD patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease Dyspnea

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Clinical Physiology Laboratory

    RECRUITING

    Edmonton, Alberta, T6G2R3, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••