Could a Two-Drug shot beat the standard for shoulder pain?

NCT ID NCT06376981

Recruiting now Symptom relief Sponsor: Centre Hospitalier Departemental Vendee Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 10, 2026 · Updated 2 times

Summary

This study tests whether adding hyaluronic acid to a standard corticosteroid injection works better for shoulder tendonitis pain than the steroid alone. About 132 adults with confirmed supraspinatus tendinopathy will receive either the combo or a placebo injection. Pain levels are checked at 1, 3, and 6 months to see which approach provides more relief.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: hyaluronic acid and corticosteroid injection
What this could lead to: If it works, this could offer a more effective injection for shoulder tendonitis pain, reducing the need for stronger treatments.
What could go wrong: This is a mid-stage trial with only 132 participants, so results may not apply to everyone. Adding hyaluronic acid may not provide extra benefit over the standard steroid shot.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

disease of the tendon tendinitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SHOULDER TENDINITIS

Contacts and locations

Locations

CHD Vendée
RECRUITING

La Roche-sur-Yon, France
CHU Nantes
RECRUITING

Nantes, France

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