Could a Two-Drug shot beat the standard for shoulder pain?

NCT ID NCT06376981

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding hyaluronic acid to a standard corticosteroid injection works better for shoulder tendonitis pain than the steroid alone. About 132 adults with confirmed supraspinatus tendinopathy will receive either the combo or a placebo injection. Pain levels are checked at 1, 3, and 6 months to see which approach provides more relief.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

hyaluronic acid and corticosteroid injection

What this could lead to

If it works, this could offer a more effective injection for shoulder tendonitis pain, reducing the need for stronger treatments.

What could go wrong

This is a mid-stage trial with only 132 participants, so results may not apply to everyone. Adding hyaluronic acid may not provide extra benefit over the standard steroid shot.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

disease of the tendon tendinitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHD Vendée

    RECRUITING

    La Roche-sur-Yon, France

    Contact

  • CHU Nantes

    RECRUITING

    Nantes, France

    Contact