Could 3 weeks of radiation be as good as 5 for breast cancer?
NCT ID NCT02912312
First seen Jan 11, 2026 · Last updated Jun 22, 2026 · Updated 30 times
Summary
This study compares a 3-week course of radiation to the standard 5-week course for breast cancer patients who need radiation to the lymph nodes. The goal is to see if the shorter schedule is just as effective at preventing cancer from coming back, while causing less arm swelling and other side effects. About 800 participants are being followed to track outcomes.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Baptist - MD Anderson Cancer Center
Jacksonville, Florida, 32207, United States
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Community MD Anderson Cancer Center East
Indianapolis, Indiana, 46219, United States
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Community MD Anderson Cancer Center North
Indianapolis, Indiana, 49625, United States
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Community MD Anderson Cancer Center South
Indianapolis, Indiana, 46227, United States
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Cooper Hospital University Medical Center
Camden, New Jersey, 08103, United States
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M D Anderson Cancer Center
Houston, Texas, 77030, United States
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MD Anderson Cancer Center (Banner)
Gilbert, Arizona, 85234, United States
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MD Anderson Cancer Center (Banner)- Northern Colorado
Greeley, Colorado, 80631, United States
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Ohio Health
Columbus, Ohio, 43215, United States
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Orlando Health Cancer Institute
Orlando, Florida, 32806, United States
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Scripps- MD Anderson Cancer
San Diego, California, 92121, United States
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UT Health San Antonio - MD Anderson Cancer Center
San Antonio, Texas, 78229, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Hypofractionated radiation therapy (shorter course of radiation)
What this could lead to
If it works, this could offer a shorter, more convenient radiation schedule for breast cancer patients, reducing arm swelling and other side effects.
What could go wrong
This is a Phase 2 trial, so results are still preliminary. The shorter schedule may not be as effective at preventing cancer recurrence, and side effects could differ.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.