Could 3 weeks of radiation be as good as 5 for breast cancer?
NCT ID NCT02912312
First seen Jun 27, 2026 · Last updated Jul 16, 2026 · Updated 2 times
Summary
This study compares a 3-week course of radiation to the standard 5-week course for breast cancer patients who need radiation to the lymph nodes. The goal is to see if the shorter schedule is just as effective at preventing cancer from coming back, while causing less arm swelling and other side effects. About 800 participants are being followed to track outcomes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Hypofractionated radiation therapy (shorter course of radiation)
- What this could lead to
- If it works, this could offer a shorter, more convenient radiation schedule for breast cancer patients, reducing arm swelling and other side effects.
- What could go wrong
- This is a Phase 2 trial, so results are still preliminary. The shorter schedule may not be as effective at preventing cancer recurrence, and side effects could differ.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Baptist - MD Anderson Cancer Center
Jacksonville, Florida, 32207, United States
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Community MD Anderson Cancer Center East
Indianapolis, Indiana, 46219, United States
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Community MD Anderson Cancer Center North
Indianapolis, Indiana, 49625, United States
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Community MD Anderson Cancer Center South
Indianapolis, Indiana, 46227, United States
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Cooper Hospital University Medical Center
Camden, New Jersey, 08103, United States
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M D Anderson Cancer Center
Houston, Texas, 77030, United States
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MD Anderson Cancer Center (Banner)
Gilbert, Arizona, 85234, United States
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MD Anderson Cancer Center (Banner)- Northern Colorado
Greeley, Colorado, 80631, United States
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Ohio Health
Columbus, Ohio, 43215, United States
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Orlando Health Cancer Institute
Orlando, Florida, 32806, United States
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Scripps- MD Anderson Cancer
San Diego, California, 92121, United States
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UT Health San Antonio - MD Anderson Cancer Center
San Antonio, Texas, 78229, United States
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