Could a shorter radiation course be just as good for endometrial cancer?
NCT ID NCT03422198
First seen Dec 17, 2025 · Last updated Jun 22, 2026 · Updated 23 times
Summary
This study compares a shorter course of vaginal cuff brachytherapy (internal radiation) to the standard longer course for people with stage I-II endometrial cancer. The main goal is to see if the shorter treatment improves quality of life and reduces financial burden, while still controlling the cancer. About 188 participants will be enrolled.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Huntsman Cancer Institute/University of Utah
RECRUITINGSalt Lake City, Utah, 84112, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Intermountain Medical Center / LDS Hospital
COMPLETEDSalt Lake City, Utah, 84143, United States
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Loyola University Medical Center
RECRUITINGMaywood, Illinois, 60153, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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MD Anderson
RECRUITINGHouston, Texas, 77030, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Stanford Cancer Center
COMPLETEDPalo Alto, California, 94304, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Vaginal cuff brachytherapy (internal radiation)
What this could lead to
If successful, this could offer a shorter, more convenient radiation treatment for early endometrial cancer, reducing side effects and improving quality of life.
What could go wrong
This is a Phase 3 trial, but it's relatively small (188 participants). The shorter course may not control cancer as well as the standard, and results may not apply to all types of endometrial cancer.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.