Hormone showdown: which progestin best tames uterine cancer before surgery?

NCT ID NCT07436793

Recruiting now Disease control Sponsor: New Mexico Cancer Research Alliance Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 1 time

Summary

This study compares two hormone drugs (megestrol acetate and micronized progesterone) in 140 women with endometrial cancer or precancer. Participants take one of the drugs for a short time before their scheduled surgery. Researchers will measure how well each drug slows cancer cell growth and look for clues about why one might work better. The goal is to improve hormone therapy for this type of cancer.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ATYPICAL ENDOMETRIAL HYPERPLASIA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

atypical endometrial hyperplasia endometrial endometrioid adenocarcinoma Endometrial Hyperplasia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ENDOMETRIAL ENDOMETRIOID ADENOCARCINOMA ENDOMETRIAL HYPERPLASIA

Contacts and locations

Locations

University of Iowa/Holden Comprehensive Cancer Center
RECRUITING

Iowa City, Iowa, 52242, United States
University of New Mexico Cancer Center
RECRUITING

Albuquerque, New Mexico, 87106, United States
University of Utah Sugarhouse Health Center
NOT_YET_RECRUITING

Salt Lake City, Utah, 84106, United States
University of Virginia Cancer Center
NOT_YET_RECRUITING

Charlottesville, Virginia, 22908, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.