Weekly shot may shield joints in hemophilia a patients

NCT ID NCT06752850

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 23 times

Summary

This study tests whether a once-weekly injection of efanesoctocog alfa can improve joint health in 37 people with moderate or severe hemophilia A. The main goal is to see if the drug reduces thickening of the joint lining (synovial hypertrophy) and prevents joint bleeds over 12 months. Participants will have regular ultrasounds and MRIs to track changes.

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Contacts and locations

Locations

  • Sobi Investigational Site

    Milan, Italy

  • Sobi Investigational Site

    Naples, Italy

  • Sobi Investigational Site

    Rozzano, Italy

  • Sobi Investigational Site

    Oslo, Norway

  • Sobi Investigational Site

    Barcelona, Spain

  • Sobi Investigational Site

    Madrid, Spain

  • Sobi Investigational Site

    Seville, Spain

  • Sobi Investigational Site

    Valencia, Spain

  • Sobi Investigational Site

    Gothenburg, Sweden

  • Sobi Investigational Site

    Malmö, Sweden

Conditions

Explore the condition pages connected to this study.