New drug shows promise in slowing kidney damage for alport syndrome patients
NCT ID NCT06274489
First seen Jan 14, 2026 · Last updated May 23, 2026 · Updated 17 times
Summary
This study tested a drug called setanaxib in 20 people with Alport syndrome, a genetic condition that damages kidneys. The goal was to see if adding setanaxib to standard care is safe and helps preserve kidney function by reducing protein in urine. Participants took either setanaxib or a placebo for 24 weeks, and researchers monitored side effects and kidney markers.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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AP-HP Hopital Necker-Enfants Malades
Paris, 75015, France
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Fakultni Nemocnice Hradec Kralove
Hradec Králové, Czechia
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Fakultni Nemocnice Olomouc
Olomouc, Czechia
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Fundacio Puigvert
Barcelona, 08025, Spain
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Great Ormond Street Hospital for Children
London, WC1N 3JH, United Kingdom
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Hospital Clinic Barcelona
Barcelona, 08036, Spain
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Hospital Fundacion Jimenez Diaz
Madrid, 28040, Spain
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Hospital Universitario 12 de Octubre
Madrid, Usera, 28041, Spain
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Hospital Universitario Reina Sofia
Córdoba, 14004, Spain
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Hospital Universitario Vall d'Hebron
Barcelona, Spain
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Hospital Universitario Virgen de las Nieves
Granada, 18014, Spain
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Institut Klinicke a Experimentalni Mediciny
Prague, Czechia
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Medizinische Universitaet Wien
Vienna, State of Vienna, 1090, Austria
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Nottingham City Hospital
Nottingham, United Kingdom
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Royal Free London NHS Foundation Trust
London, NW3 2QG, United Kingdom
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Royal Manchester Children's Hospital
Manchester, M13 9WL, United Kingdom
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Vseobecna Fakultni Nemocnice v Praze
Prague, Czechia
Conditions
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