Cure My Disease

Don't miss your cure!

 Log in / Sign up

New drug aims to slow kidney damage in rare alport syndrome

NCT ID NCT07523581

Recruiting now Disease control Sponsor: Eloxx Pharmaceuticals, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 16, 2026 · Updated 5 times

Summary

This study tests a drug called exaluren in 24 people aged 12 and older with Alport syndrome caused by specific genetic errors. The drug is given as a daily shot for 32 weeks. Half the group starts exaluren right away, while the other half gets a placebo first and then switches to exaluren. The goal is to see if exaluren can improve kidney health by looking at tiny changes in kidney tissue and protein levels in urine.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ALPORT SYNDROME are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Alport syndrome autosomal recessive Alport syndrome hereditary nephritis X-linked Alport syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALPORT SYNDROME, AUTOSOMAL RECESSIVE ALPORT SYNDROME, X-LINKED

Contacts and locations

Locations

  • Alder Hey Children's NHS Foundation Trust

    NOT_YET_RECRUITING

    Liverpool, L12 2AP, United Kingdom

  • Cleveland Clinic

    NOT_YET_RECRUITING

    Cleveland, Ohio, 44195, United States

  • Denver Nephrologists PC, Colorado Kidney Care PC

    RECRUITING

    Denver, Colorado, 80220, United States

  • Great Ormond Street Hospital

    RECRUITING

    London, WC1N 3JH, United Kingdom

  • Hackensack University Medical Center

    NOT_YET_RECRUITING

    Hackensack, New Jersey, 07601, United States

  • Renal Associates, P.A.

    NOT_YET_RECRUITING

    San Antonio, Texas, 78109, United States

  • Royal Free Hospital

    RECRUITING

    London, NW3 2QG, United Kingdom

  • Royal Manchester Children's Hospital

    NOT_YET_RECRUITING

    Manchester, M13 9WL, United Kingdom

  • Stanford University

    NOT_YET_RECRUITING

    Stanford, California, 94305, United States

  • University of California, Los Angeles

    NOT_YET_RECRUITING

    Los Angeles, California, 90095, United States

    Contact Email: •••••@•••••

  • University of Minnesota

    NOT_YET_RECRUITING

    Minneapolis, Minnesota, 55455, United States

  • University of Pennsylvania

    NOT_YET_RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.