New drug aims to slow kidney damage in rare alport syndrome
NCT ID NCT07523581
First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 1 time
Summary
This study tests a drug called exaluren in 24 people aged 12 and older with Alport syndrome caused by specific genetic errors. The drug is given as a daily shot for 32 weeks. Half the group starts exaluren right away, while the other half gets a placebo first and then switches to exaluren. The goal is to see if exaluren can improve kidney health by looking at tiny changes in kidney tissue and protein levels in urine.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Alder Hey Children's NHS Foundation Trust
Liverpool, L12 2AP, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Cleveland Clinic
Cleveland, Ohio, 44195, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Denver Nephrologists PC, Colorado Kidney Care PC
Denver, Colorado, 80220, United States
Contact Email: •••••@•••••
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Great Ormond Street Hospital
London, WC1N 3JH, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hackensack University Medical Center
Hackensack, New Jersey, 07601, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Renal Associates, P.A.
San Antonio, Texas, 78109, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Royal Free Hospital
London, NW3 2QG, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Royal Manchester Children's Hospital
Manchester, M13 9WL, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Stanford University
Stanford, California, 94305, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of California, Los Angeles
Los Angeles, California, 90095, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Minnesota
Minneapolis, Minnesota, 55455, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••