New drug combo could slow kidney failure in rare genetic disease
NCT ID NCT06499948
First seen Apr 25, 2026 · Last updated Apr 30, 2026 · Updated 1 time
Summary
This study tests whether two common drugs—dapagliflozin and spironolactone—can reduce protein in the urine of adults with Alport syndrome, a genetic kidney disease that often leads to kidney failure. About 34 participants will try each drug alone and then together, adding them to their usual treatment. The goal is to see if this combination can better protect kidney function and delay the need for dialysis or transplant.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Fundeni Clinical Institute
Bucharest, Sector 2, 020021, Romania
Conditions
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