Can an amino acid boost chemo? early trial launches for advanced colorectal cancer
NCT ID NCT07178613
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 2 times
Summary
This early-stage trial is testing whether adding oral serine, a natural amino acid, to standard chemotherapy is safe for people with advanced colorectal cancer. The study will enroll 20 adults who are eligible for first-line treatment with fluorouracil-based drugs. The main goal is to check for side effects and find the best dose of serine to use in future studies.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
serine (an amino acid) taken orally alongside standard chemotherapy drugs (fluoropyrimidines)
What this could lead to
If successful, this could point toward a way to make standard chemotherapy more effective or less toxic for people with advanced colorectal cancer.
What could go wrong
This is a very early Phase 1 trial with only 20 people. The main goal is safety, not yet proof that it works. It may not show any benefit or could cause unexpected side effects.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ADVANCED COLORECTAL CANCER are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.