Breath, blood, and saliva tests could replace sputum for CF lung infections
NCT ID NCT07312734
First seen Jan 04, 2026 · Last updated Jun 19, 2026 · Updated 26 times
Summary
This study looks for better ways to find harmful bacteria in the lungs of people with cystic fibrosis. Traditional sputum tests are becoming harder to use because newer CF treatments reduce mucus. Researchers will collect samples like saliva, blood, urine, and breath from 300 participants to see if these can reliably detect infections.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Froedtert & Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
Contact Email: •••••@•••••
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Nationwide Children's Hospital
Columbus, Ohio, 43205, United States
Contact Email: •••••@•••••
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The Minnesota Cystic Fibrosis Center
Minneapolis, Minnesota, 55455, United States
Contact Email: •••••@•••••
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University of California San Diego
La Jolla, California, 92037, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Nebraska Medical Center
Omaha, Nebraska, 69198, United States
Contact Email: •••••@•••••
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
Contact Email: •••••@•••••
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University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, 15224, United States
Contact Email: •••••@•••••
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University of Texas Southwestern
Dallas, Texas, 75390, United States
Contact Email: •••••@•••••
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Washington University School of Medicine
St Louis, Missouri, 63110, United States
Contact Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could lead to better, easier diagnostic tests for lung infections in people with cystic fibrosis, especially those who cannot produce sputum.
What could go wrong
This is an observational study, not a treatment trial. It may not directly improve health outcomes, and new tests may not prove more accurate than current methods.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.