Semaglutide users may face hidden surgery risk, ultrasound study finds

NCT ID NCT06263595

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study used ultrasound to measure stomach contents in 94 patients before surgery, comparing those on semaglutide (a GLP-1 drug for diabetes/weight loss) to those not taking it. The goal was to see if semaglutide increases the risk of a 'full stomach' despite following fasting rules, which could lead to dangerous aspiration during anesthesia. Researchers hope the findings will help create safer fasting guidelines for these patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

semaglutide

What this could lead to

If successful, this could lead to better fasting guidelines for patients on semaglutide before surgery, reducing the risk of aspiration pneumonia.

What could go wrong

This is a small, completed observational study (94 participants) that only measures stomach volume, not actual aspiration events. Results may not apply to all patients or settings.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

aspiration pneumonia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • South Health Campus

    Calgary, Alberta, T3M 1M4, Canada