New study tests if a liquid diet can prevent dangerous aspiration in patients on popular diabetes drugs

NCT ID NCT06654219

First seen Jun 25, 2026 · Last updated Aug 05, 2026 · Updated 3 times

Summary

This study looks at whether a clear liquid diet for 24 hours before anesthesia can reduce leftover stomach contents in patients taking GLP-1 drugs (like Ozempic). These drugs slow digestion, which can increase the risk of food or liquid entering the lungs during anesthesia. The study will compare two groups: one that follows the liquid diet and one that fasts normally. Researchers will measure stomach contents using ultrasound and check for side effects like thirst and hunger.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
clear liquid diet
What this could lead to
If successful, this could lead to safer fasting guidelines for patients on GLP-1 drugs before procedures, reducing the risk of lung aspiration.
What could go wrong
This is a small, early-phase study (136 participants) that only measures stomach contents, not actual aspiration events. Results may not apply to all patients or procedures.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The University of Texas Health Science Center at Houston

    RECRUITING

    Houston, Texas, 77030, United States

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