To fast or not to fast? major trial tests Tube-Feeding timing in ICU

NCT ID NCT06751043

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether stopping tube feeding for at least 8 hours before a procedure helps or harms recovery in critically ill patients on breathing machines. About 1,072 adults in the ICU will be randomly assigned to either fast or continue feeding until right before their procedure. Researchers will track lung complications, hospital stays, and survival to see which approach is safer.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CRITICAL ILLNESS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

aspiration pneumonia Critical Illness Fasting

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Brigham & Women's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact

  • Cleveland Clinic

    ACTIVE_NOT_RECRUITING

    Cleveland, Ohio, 44195, United States

  • Columbia University Irvine Medical Center

    RECRUITING

    New York, New York, 10032, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mass General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact

  • McGaw Medical Center of Northwestern

    RECRUITING

    Chicago, Illinois, 60611, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Montefiore Medical Center

    RECRUITING

    The Bronx, New York, 10467, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Rush University Medical Center

    RECRUITING

    Chicago, Illinois, 60612, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Stanford Medical Center

    RECRUITING

    Palo Alto, California, 94305, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UCSF Medical Center Parnassus

    RECRUITING

    San Francisco, California, 94143, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UT Health Houston

    NOT_YET_RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Colorado Medical Center

    NOT_YET_RECRUITING

    Aurora, Colorado, 80045, United States

    Contact Phone: •••-•••-••••

  • University of Maryland Medical Center

    NOT_YET_RECRUITING

    Baltimore, Maryland, 21201, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Massachusetts Memorial Medical Center

    RECRUITING

    Worcester, Massachusetts, 01655, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Miami Hospital

    NOT_YET_RECRUITING

    Miami, Florida, 33136, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Minnesota Medical Center

    RECRUITING

    Minneapolis, Minnesota, 55455, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Rochester Medical Center

    NOT_YET_RECRUITING

    Rochester, New York, 14642, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Texas Medical Branch

    RECRUITING

    Galveston, Texas, 77555, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Wake Forest University Health Sciences

    RECRUITING

    Winston-Salem, North Carolina, 27103, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

More trials for these conditions

Other studies related to the condition(s) this trial covers.