New combo therapy shows promise for older leukemia patients

NCT ID NCT02835222

First seen Jan 04, 2026 · Last updated May 15, 2026 · Updated 17 times

Summary

This study tests whether adding the drug selinexor to standard chemotherapy helps older adults with untreated acute myeloid leukemia (AML) live longer. About 57 participants will receive either chemo alone or chemo plus selinexor, followed by maintenance therapy. The goal is to see if the combination improves survival and remission rates.

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Contacts and locations

Locations

  • Comprehensive Cancer Center of Wake Forest University

    Winston-Salem, North Carolina, 27157, United States

  • Virginia Commonwealth University Massey Cancer Center

    Richmond, Virginia, 23298, United States

Conditions

Explore the condition pages connected to this study.