New cream could help kids with 'Butterfly Skin' heal faster

NCT ID NCT07482787

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 trial tests whether a cream called SD-101 can help close wounds in children with epidermolysis bullosa (EB), a condition that causes fragile, blistering skin. About 80 children aged 1 month to 12 years will apply the cream or a placebo to their whole body for 2 months. The main goal is to see if the cream helps a target wound close completely within one month.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

SD-101 (allantoin) cream

What this could lead to

If it works, this could provide a safe, at-home cream to help close wounds faster in children with epidermolysis bullosa.

What could go wrong

This is still a placebo-controlled trial, so it's not yet proven to work. The cream may not be more effective than placebo, and results may not apply to all types of EB.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

epidermolysis bullosa epidermolysis bullosa simplex junctional epidermolysis bullosa, non-Herlitz type Pruritus recessive dystrophic epidermolysis bullosa

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

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