Can a birch bark gel soothe blistering skin disease?
NCT ID NCT07756138
First seen Aug 10, 2026 · Last updated Aug 11, 2026 · Updated 1 time
Summary
This pilot trial is testing whether a topical gel called Filsuvez, made from birch triterpenes, is safe and helpful for people aged 6 months and older with moderate-to-severe epidermolysis bullosa simplex (EBS), a condition causing fragile skin and blisters. Participants will apply the gel to about 3% of their body surface for three months. The study aims to see if the gel reduces blistering, helps wounds heal faster, and improves comfort by lessening pain and itching.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Filsuvez (birch triterpenes) topical gel
- What this could lead to
- If successful, this could point toward a new topical treatment to reduce blistering, speed wound healing, and ease pain and itching for people with epidermolysis bullosa simplex.
- What could go wrong
- This is a small pilot study with only 10 participants, so results may not apply broadly. The gel's effectiveness and safety are still uncertain, and it may not work for everyone.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Stanford University School of Medicine
Palo Alto, California, 94304, United States
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