New hope for blistering skin diseases: drug targets antibodies to heal wounds
NCT ID NCT07011589
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase study tests whether the drug efgartigimod (VYVGART) can lower harmful collagen VII antibodies and improve wound healing in people with two rare blistering skin conditions: recessive dystrophic epidermolysis bullosa (RDEB) and epidermolysis bullosa acquisita (EBA). About 18 participants aged 12 and older will receive the drug intravenously, and those with RDEB will also receive a topical gene therapy (VYJUVEK) on one wound. The goal is to see if reducing these antibodies leads to fewer wounds and better quality of life.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Stanford University
Redwood City, California, 94163, United States
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