Turmeric and blue light may heal blisters in rare skin disease

NCT ID NCT07596927

First seen Jun 24, 2026 · Last updated Jul 17, 2026 · Updated 3 times

Summary

This study tests whether a gel made from curcumin (the active part of turmeric) combined with blue LED light can heal painful mouth blisters in people with epidermolysis bullosa, a rare condition that makes skin and mucous membranes extremely fragile. Twenty participants will receive the treatment for three days, and researchers will track how well the blisters heal and whether quality of life improves. The study also looks for biomarkers in saliva that could help diagnose or monitor the disease without needing a biopsy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
curcumin gel with blue LED light
What this could lead to
If it works, this could offer a simple, non-invasive way to heal painful mouth blisters and improve daily life for people with epidermolysis bullosa.
What could go wrong
This is a very small study (20 people) with no placebo group, so results may not apply widely. The treatment is short-term and only targets oral lesions, not the underlying disease.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Rua Perdizes, Quadra 35, n. 27/805, Jardim Renascença

    São Luís, Maranhão, 65075340, Brazil

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