New radiation method aims to protect scalp in brain tumor patients
NCT ID NCT03251027
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a precise type of radiation therapy (IM-SRT) for people with newly diagnosed grade II to IV gliomas. The goal is to deliver a high dose of radiation directly to the tumor while minimizing damage to the scalp, which may reduce wound infections and the need for metal implants after surgery. About 100 participants will receive this treatment and be monitored for complications and quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Intensity-modulated stereotactic radiotherapy (IM-SRT)
- What this could lead to
- If successful, this approach could reduce wound infections and the need for titanium implants after brain tumor surgery, improving recovery and quality of life.
- What could go wrong
- This is a single-arm phase II trial with 100 participants, so results may not apply to all patients. The technique may not control the tumor as well as standard radiation, and scalp-sparing benefits are not yet proven.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Sidney Kimmel Cancer Center at Thomas Jefferson University
Philadelphia, Pennsylvania, 19107, United States
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