New radiation method aims to protect scalp in brain tumor patients

NCT ID NCT03251027

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a precise type of radiation therapy (IM-SRT) for people with newly diagnosed grade II to IV gliomas. The goal is to deliver a high dose of radiation directly to the tumor while minimizing damage to the scalp, which may reduce wound infections and the need for metal implants after surgery. About 100 participants will receive this treatment and be monitored for complications and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Intensity-modulated stereotactic radiotherapy (IM-SRT)

What this could lead to

If successful, this approach could reduce wound infections and the need for titanium implants after brain tumor surgery, improving recovery and quality of life.

What could go wrong

This is a single-arm phase II trial with 100 participants, so results may not apply to all patients. The technique may not control the tumor as well as standard radiation, and scalp-sparing benefits are not yet proven.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

glioblastoma grade II glioma grade III glioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sidney Kimmel Cancer Center at Thomas Jefferson University

    Philadelphia, Pennsylvania, 19107, United States