New drug combo shows promise for Hard-to-Treat breast cancer

NCT ID NCT06100874

First seen Feb 21, 2026 · Last updated May 13, 2026 · Updated 14 times

Summary

This study tests a combination of two drugs, sacituzumab govitecan and trastuzumab, in 28 people with HER2+ breast cancer that has spread and has been previously treated. The goal is to see if this combination can shrink tumors or slow cancer growth. Participants receive both drugs intravenously, and the study tracks how many respond and how long the benefit lasts.

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Contacts and locations

Locations

  • DFCI @ South Shore Hospital

    South Weymouth, Massachusetts, 02190, United States

  • Dana Farber Cancer Institite

    Boston, Massachusetts, 02215, United States

  • Miami Cancer Institute at Baptist Health

    Miami, Florida, 33176, United States

  • SCRI Oncology Partners

    Nashville, Tennessee, 37203, United States

Conditions

Explore the condition pages connected to this study.