Could a wearable ultrasound device ease knee arthritis pain without drugs?

NCT ID NCT07515872

Not yet recruiting Symptom relief Sponsor: ZetrOZ, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tests a wearable device that delivers continuous ultrasound to the knee for 1-4 hours daily, with or without a diclofenac pain patch, compared to a standard steroid injection. 240 adults aged 65-85 with mild to moderate knee osteoarthritis will use the device at home for 12 weeks. The goal is to see if the ultrasound treatment reduces pain and improves joint function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ultrasound device with or without diclofenac patch
What this could lead to: If it works, this could offer a non-invasive, drug-free option for managing knee osteoarthritis pain at home.
What could go wrong: This is an early phase 2 trial with 240 participants, so results may not apply to everyone. The device requires daily use for hours, which may be inconvenient.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ARTHRITIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

arthritic joint disease osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ARTHRITIS OSTEO ARTHRITIS OF THE KNEE

Contacts and locations

Locations

Cayuga Medical Center - Medical Pain Consultants

Dryden, New York, 13053, United States
Orthopaedic Foundation

Stamford, Connecticut, 06905, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.