Which IV fluid is safer for heat stroke? study investigates
NCT ID NCT05921695
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at whether using Ringer's lactate instead of normal saline during emergency treatment for heat stroke could reduce the risk of acute kidney injury. Researchers planned to enroll 104 adults diagnosed with heat stroke, giving one group standard saline and the other group Ringer's lactate. The goal was to see if limiting high-chlorine fluids like saline lowers kidney damage and death rates. The trial was terminated early, so results are limited.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
normal saline and Ringer's lactate
What this could lead to
If this study yields clear results, it could help emergency doctors choose the best fluid to prevent kidney damage in heat stroke patients.
What could go wrong
The trial was terminated early, so results may be incomplete. It is a small, single-center study, so findings may not apply broadly.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Dongyang People's Hospital
Dongyang, China
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Jinhua Municipal Central Hospital
Jinhua, China
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Jinhua People's Hospital
Jinhua, China
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Lanxi People's Hospital
Lanxi, China
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The Second Affiliated Hospital of Zhejiang University School of Medicine
Hangzhou, 310000, China
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Yiwu Central Hospital
Yiwu, Zhejiang, China
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YongKang First People's Hospital
Guli, Zhejiang, 321300, China