Which IV fluid is safer for heat stroke? study investigates

NCT ID NCT05921695

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether using Ringer's lactate instead of normal saline during emergency treatment for heat stroke could reduce the risk of acute kidney injury. Researchers planned to enroll 104 adults diagnosed with heat stroke, giving one group standard saline and the other group Ringer's lactate. The goal was to see if limiting high-chlorine fluids like saline lowers kidney damage and death rates. The trial was terminated early, so results are limited.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
normal saline and Ringer's lactate
What this could lead to
If this study yields clear results, it could help emergency doctors choose the best fluid to prevent kidney damage in heat stroke patients.
What could go wrong
The trial was terminated early, so results may be incomplete. It is a small, single-center study, so findings may not apply broadly.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Dongyang People's Hospital

    Dongyang, China

  • Jinhua Municipal Central Hospital

    Jinhua, China

  • Jinhua People's Hospital

    Jinhua, China

  • Lanxi People's Hospital

    Lanxi, China

  • The Second Affiliated Hospital of Zhejiang University School of Medicine

    Hangzhou, 310000, China

  • Yiwu Central Hospital

    Yiwu, Zhejiang, China

  • YongKang First People's Hospital

    Guli, Zhejiang, 321300, China

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