Could fewer radiation sessions help glioblastoma patients live longer?

NCT ID NCT05781321

First seen Nov 01, 2025 · Last updated May 10, 2026 · Updated 24 times

Summary

This study compares a short course of high-dose radiation to the standard longer course for people with glioblastoma, an aggressive brain cancer. The goal is to see if the shorter treatment is just as effective at keeping patients alive at 12 months while possibly causing fewer side effects. About 170 adults with confirmed glioblastoma will take part.

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Contacts and locations

Locations

  • Mayo Clinic Health System in Albert Lea

    Albert Lea, Minnesota, 56007, United States

  • Mayo Clinic Health System-Eau Claire

    Eau Claire, Wisconsin, 54701, United States

  • Mayo Clinic Health System-Franciscan Healthcare

    La Crosse, Wisconsin, 54601, United States

  • Mayo Clinic Health Systems-Mankato

    Mankato, Minnesota, 56001, United States

  • Mayo Clinic Radiation Therapy - Northfield

    Northfield, Minnesota, 55057, United States

  • Mayo Clinic in Arizona

    Scottsdale, Arizona, 85259, United States

  • Mayo Clinic in Florida

    Jacksonville, Florida, 32224-9980, United States

  • Mayo Clinic in Rochester

    Rochester, Minnesota, 55905, United States

Conditions

Explore the condition pages connected to this study.