Can a tree bark extract boost brain health and lower blood sugar?
NCT ID NCT07220694
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This 8-week study tests whether a daily supplement called Sabroxy® (made from Oroxylum indicum bark) can improve insulin resistance and memory in adults aged 40-80 with mild cognitive impairment and insulin resistance. About 140 participants will receive either Sabroxy® or a placebo. Researchers will measure changes in insulin resistance, cognitive test scores, and blood markers of inflammation and brain health.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Sabroxy® (Oroxylum indicum bark extract with BioPerine® black pepper extract)
What this could lead to
If it works, this could point toward a natural supplement option to help manage early cognitive decline and insulin resistance.
What could go wrong
This is a small, early-stage trial (140 participants, 8 weeks) with no prior strong evidence. The supplement may show no benefit over placebo, and individual results may vary.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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San Francisco Research Institute
RECRUITINGSan Francisco, California, 94132, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••