Can a tree bark extract boost brain health and lower blood sugar?
NCT ID NCT07220694
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This 8-week study tests whether a daily supplement called Sabroxy® (made from Oroxylum indicum bark) can improve insulin resistance and memory in adults aged 40-80 with mild cognitive impairment and insulin resistance. About 140 participants will receive either Sabroxy® or a placebo. Researchers will measure changes in insulin resistance, cognitive test scores, and blood markers of inflammation and brain health.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Sabroxy® (Oroxylum indicum bark extract with BioPerine® black pepper extract)
- What this could lead to
- If it works, this could point toward a natural supplement option to help manage early cognitive decline and insulin resistance.
- What could go wrong
- This is a small, early-stage trial (140 participants, 8 weeks) with no prior strong evidence. The supplement may show no benefit over placebo, and individual results may vary.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
San Francisco Research Institute
RECRUITINGSan Francisco, California, 94132, United States
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