New Helmet-Style brain stimulation may beat standard treatment for resistant depression

NCT ID NCT04956016

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a newer 'deep' magnetic stimulation helmet works better than the standard coil for people with depression that hasn't improved with medication. 152 adults will receive 20 sessions over 4 weeks and be followed for 90 days. The goal is to see which method reduces depression symptoms more effectively.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

rTMS (repetitive transcranial magnetic stimulation) using either a standard 8-shaped coil or a deep H1-shaped coil

What this could lead to

If deep rTMS proves more effective, it could offer a better non-drug option for people with depression that hasn't responded to medication.

What could go wrong

This is a relatively small, early-stage comparative study. The results may not apply to all patients, and neither treatment is guaranteed to work for everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

depressive disorder Depressive Disorder, Treatment-Resistant

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre Hospitalier Henri Laborit

    RECRUITING

    Poitiers, France

    Contact