New Helmet-Style brain stimulation may beat standard treatment for resistant depression

NCT ID NCT04956016

Recruiting now Symptom relief Sponsor: Centre Hospitalier Henri Laborit Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a newer 'deep' magnetic stimulation helmet works better than the standard coil for people with depression that hasn't improved with medication. 152 adults will receive 20 sessions over 4 weeks and be followed for 90 days. The goal is to see which method reduces depression symptoms more effectively.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: rTMS (repetitive transcranial magnetic stimulation) using either a standard 8-shaped coil or a deep H1-shaped coil
What this could lead to: If deep rTMS proves more effective, it could offer a better non-drug option for people with depression that hasn't responded to medication.
What could go wrong: This is a relatively small, early-stage comparative study. The results may not apply to all patients, and neither treatment is guaranteed to work for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for DEPRESSIVE DISORDER, TREATMENT-RESISTANT are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

depressive disorder Depressive Disorder, Treatment-Resistant

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEPRESSIVE DISORDER, TREATMENT-RESISTANT

Contacts and locations

Locations

Centre Hospitalier Henri Laborit
RECRUITING

Poitiers, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.