Can magnetic pulses rewire the schizophrenic brain?

NCT ID NCT07772349

First seen Aug 19, 2026 ยท Last updated Aug 19, 2026

Summary

This study tests whether combining repetitive transcranial magnetic stimulation (rTMS) with cognitive training games can strengthen brain connections in people with schizophrenia. Participants will receive either active or sham rTMS sessions along with computer-based cognitive exercises over about two weeks. The researchers will use MRI and EEG to measure changes in brain structure and activity, aiming to see if this approach can improve brain health and function.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Repetitive transcranial magnetic stimulation (rTMS) with an H4 coil, combined with cognitive training games
What this could lead to
If successful, this could point toward a non-invasive treatment that improves brain connectivity and cognitive function in people with schizophrenia.
What could go wrong
This is an early-stage trial, and the effects on brain scans may not translate into real-world improvements. rTMS can cause mild discomfort or, rarely, seizures.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The University of Texas Health Science Center, Houston

    Houston, Texas, 77054, United States

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