New mRNA vaccine targets RSV in first human trial

NCT ID NCT06573281

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This early-stage trial is testing several doses of an experimental mRNA vaccine against RSV in 213 healthy adults aged 18-45. The goal is to check the vaccine's safety and how well it triggers an immune response. Participants receive two shots, and researchers monitor for side effects and measure antibody levels.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

mRNA-based RSV vaccine

What this could lead to

If successful, this could lead to a new vaccine to protect against RSV, a common respiratory virus that can be serious for infants and older adults.

What could go wrong

This is an early Phase 1 trial with only 213 healthy adults, so safety and immune response are still being tested. It may not work in larger, more diverse populations or against different RSV strains.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

respiratory syncytial virus infectious disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • GSK Investigational Site

    Rolling Hills Estates, California, 90274, United States

  • GSK Investigational Site

    Atlanta, Georgia, 30281, United States

  • GSK Investigational Site

    Lenexa, Kansas, 66219, United States

  • GSK Investigational Site

    Omaha, Nebraska, 68134, United States

  • GSK Investigational Site

    Rochester, New York, 14609, United States

  • GSK Investigational Site

    Camberwell, Victoria, 3124, Australia

  • GSK Investigational Site

    Madrid, 28006, Spain

  • GSK Investigational Site

    Madrid, 28046, Spain

  • GSK Investigational Site

    Madrid, 28222, Spain