Could a common cholesterol drug protect bones and hearts after spinal injury?
NCT ID NCT03113994
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether the statin drug rosuvastatin, taken daily with supplements, could improve bone density and reduce heart disease risk in adults with long-term spinal cord injury. Only 8 people enrolled before the trial was stopped early. Participants received either rosuvastatin or a placebo, plus coenzyme Q10, calcium, and vitamin D, for 12 months. The main goal was to see changes in knee bone density and cholesterol levels.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Rosuvastatin (a statin drug) plus coenzyme Q10, calcium, and vitamin D supplements
- What this could lead to
- If it works, this could point toward a way to reduce bone loss and heart disease risk in people with spinal cord injury.
- What could go wrong
- This was a very small, early-phase trial that was terminated early, so results are limited. Statins can cause muscle or liver problems, and the benefits seen may not apply to everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University Health Network - Toronto Rehab Lyndhurst Centre
Toronto, Ontario, M4G 3V9, Canada
-
University Of Miami Miller School of Medicine
Miami, Florida, 33136, United States
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