New study tests better ways to clean teeth during root canal retreatment

NCT ID NCT07150585

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looks at three different methods to activate cleaning fluids during root canal retreatment: ultrasonic, sonic, and laser. The goal is to see which one causes the least pain and helps the infection heal best. Seventy-five adults with previously treated teeth that still have small infections are taking part. Pain is measured over a week, and healing is checked with X-rays up to two years later.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could identify the best irrigation activation method to reduce pain and improve healing after root canal retreatment.
What could go wrong
This is a small, early-stage study with only 75 participants, so results may not apply to all patients. The outcomes rely on subjective pain reports and radiographic healing, which can vary.

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Conditions

The condition(s) this trial relates to.

chronic apical periodontitis Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ege University, Department of Endodontics

    Izmır, Bornova, Turkey (Türkiye)

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