Dentists test three sealers to find the most comfortable root canal

NCT ID NCT07608939

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares three different root canal sealers—AH Plus, ProRoot Bio Sealer, and BC Sealer ion+—to see which one leads to the least pain after treatment. About 135 adults with irreversible pulpitis in a lower molar will be randomly assigned to one of the three sealers. Patients and the pain assessor won't know which sealer was used. Pain is measured over a week using a 0-10 scale.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Root canal sealers (AH Plus, ProRoot Bio Sealer, BC Sealer ion+)

What this could lead to

If one sealer consistently causes less pain, dentists may adopt it to make root canals more comfortable.

What could go wrong

This is a small, early-stage study (135 people) comparing existing materials, so results may not apply to all patients or change practice.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative pulpitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.