Tooth treatment may cut heart inflammation, small trial hints

NCT ID NCT07343804

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether root canal treatment can reduce inflammation markers linked to heart disease in people with stable coronary artery disease and infected tooth roots. Eighty adults will either get immediate root canal treatment or wait three months. Researchers will measure blood levels of hs-CRP and IL-6 to see if treating the tooth infection lowers heart risk.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

root canal treatment

What this could lead to

If successful, this could show that treating tooth infections reduces inflammation and may lower heart disease risk.

What could go wrong

This is a small, early-stage study with only 80 participants. It measures biomarkers, not actual heart events, so real-world benefits remain uncertain.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder chronic apical periodontitis coronary artery disorder periapical periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Post Graduate institute of Dental Sciences, Rohtak

    RECRUITING

    Rohtak, Haryana, 124001, India

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••