Tooth treatment may cut heart inflammation, small trial hints

NCT ID NCT07343804

Recruiting now Knowledge-focused Sponsor: Postgraduate Institute of Dental Sciences Rohtak Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether root canal treatment can reduce inflammation markers linked to heart disease in people with stable coronary artery disease and infected tooth roots. Eighty adults will either get immediate root canal treatment or wait three months. Researchers will measure blood levels of hs-CRP and IL-6 to see if treating the tooth infection lowers heart risk.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: root canal treatment
What this could lead to: If successful, this could show that treating tooth infections reduces inflammation and may lower heart disease risk.
What could go wrong: This is a small, early-stage study with only 80 participants. It measures biomarkers, not actual heart events, so real-world benefits remain uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder chronic apical periodontitis coronary artery disorder periapical periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIOVASCULAR DISEASE RISK FACTOR PERIAPICAL PERIODONTITIS

Contacts and locations

Locations

Post Graduate institute of Dental Sciences, Rohtak
RECRUITING

Rohtak, Haryana, 124001, India

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