Bone-Building drug combo shows promise for spinal cord injury patients
NCT ID NCT04232657
First seen Apr 26, 2026 · Last updated Jun 10, 2026 · Updated 9 times
Summary
This study tests whether a two-step drug treatment can improve bone density in people with chronic spinal cord injury (SCI) who have bone loss below the injury level. Participants receive either romosozumab (a bone-building drug) or a placebo for 12 months, followed by denosumab (a bone-maintaining drug) for another 12 months. The goal is to see if this approach can safely increase and then preserve bone strength. The study involves 36 adults with long-term SCI.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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James J. Peters VA Medical Center, Bronx, NY
The Bronx, New York, 10468-3904, United States
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Kessler Institute for Rehabilitation
West Orange, New Jersey, 07052, United States
Conditions
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