THC brain study aims to uncover why some people react differently to cannabis
NCT ID NCT06758596
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 27 times
Summary
This early-phase study will give 144 healthy young adults (ages 18-21) a single dose of THC (7.5 mg) or a placebo capsule, then measure their brain activity using fMRI and track their mood and behavior. The goal is to understand why some people respond differently to cannabis, which could eventually help prevent or treat substance use disorders. The study is not yet recruiting participants.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Illinois at Chicago
Chicago, Illinois, 60612, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
THC (tetrahydrocannabinol) in a capsule
What this could lead to
If successful, this study could help explain why some people react differently to cannabis, potentially guiding personalized prevention or treatment for substance use disorders.
What could go wrong
This is a very early, small study (144 participants) focused on healthy young adults, so findings may not apply to the general population or those with severe substance use disorders. The study is not yet recruiting.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.