Blood filtering may heal rare skin wounds in kidney patients
NCT ID NCT04654000
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a blood filtering procedure called rheopheresis to treat calciphylaxis, a rare condition causing painful skin wounds in people on dialysis. About 138 participants will receive either rheopheresis or a sham procedure to see if it helps wounds heal completely within 12 weeks. The goal is to find a better way to manage this serious complication.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Rheopheresis procedure (a blood filtering treatment)
- What this could lead to
- If it works, this could offer a new way to help heal painful skin wounds in dialysis patients with calciphylaxis, improving their quality of life.
- What could go wrong
- This is a small, early-stage trial with only 138 participants. The treatment is complex and may not work for everyone, and there are risks from the procedure itself.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CH de Boulogne sur Mer
RECRUITINGBoulogne-sur-Mer, 62321, France
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CH de Béthune
RECRUITINGBéthune, 62408, France
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CH de Niort
NOT_YET_RECRUITINGNiort, 79000, France
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CH de Valenciennes
RECRUITINGValenciennes, 59300, France
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CH de Vichy
NOT_YET_RECRUITINGVichy, 03200, France
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CHR de Limoges
RECRUITINGLimoges, 87042, France
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CHRU de Brest
NOT_YET_RECRUITINGBrest, 29609, France
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CHRU de Nancy Brabois
NOT_YET_RECRUITINGVandœuvre-lès-Nancy, 54500, France
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CHU d'Angers
NOT_YET_RECRUITINGAngers, 49933, France
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CHU d'Arras
RECRUITINGArras, 62022, France
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CHU d'Auxerre
NOT_YET_RECRUITINGAuxerre, 89011, France
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CHU de Besançon, Hôpital Jean Minjoz
RECRUITINGBesançon, 25000, France
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CHU de Bordeaux
NOT_YET_RECRUITINGBourdeaux, 33076, France
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CHU de Caen
NOT_YET_RECRUITINGCaen, 14033, France
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CHU de Montpellier
RECRUITINGMontpellier, 34295, France
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CHU de Nantes
RECRUITINGNantes, 44093, France
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CHU de Reims
RECRUITINGReims, 51092, France
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CHU de Toulouse
RECRUITINGToulouse, 31059, France
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Centre ECHO Laval
RECRUITINGLaval, 53015, France
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Centre ECHO Le Mans
RECRUITINGLe Mans, 72000, France
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Centre Hospitalier Bretagne Atlantique
NOT_YET_RECRUITINGVannes, 56017, France
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Clinique Saint Exupéry
NOT_YET_RECRUITINGToulouse, 31400, France
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Hop Claude Huriez Chu Lille
RECRUITINGLille, France
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Hôpital Lyon Sud
NOT_YET_RECRUITINGLyon, 69495, France
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Hôpital Nord Michallon, CHU de Grenoble
RECRUITINGGrenoble, 38043, France
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Hôpital Privé La Louvière
RECRUITINGLille, 59000, France
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Hôpital Saint Joseph Saint Luc
NOT_YET_RECRUITINGLyon, 69635, France
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Hôpital de la Conception, AP-HM
RECRUITINGMarseille, 13385, France
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Institut Phocéen de Néphrologie - Clinique Bouchard
NOT_YET_RECRUITINGMarseille, 13006, France
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Other studies related to the condition(s) this trial covers.
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- What does life feel like for children with a rare birth defect? a new study asks
- AI therapy coach aims to ease distress in seriously ill seniors
- A simple stretch during dialysis might soothe restless legs
- One-shot gene editor aims to correct a brain disorder at its source
- A regenerative graft could rethink dialysis access