New combo therapy shows promise for tough brain cancers
NCT ID NCT03532295
First seen Nov 21, 2025 · Last updated Apr 28, 2026 · Updated 22 times
Summary
This study tested a mix of two immune-boosting drugs (retifanlimab and epacadostat) plus radiation and a targeted therapy (bevacizumab) in 51 adults with recurrent glioblastoma, an aggressive brain cancer. The goal was to see if this combination could help the immune system attack the tumor and improve survival. The trial has been completed, and results are being analyzed.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Mayo Clinic
Phoenix, Arizona, 85259, United States
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Mayo Clinic
Rochester, Minnesota, 55905, United States
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Wake Forest Baptist Medical Center
Winston-Salem, North Carolina, 27157, United States
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Washington University School of Medicine
St Louis, Missouri, 63110, United States
Conditions
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