New weekly shot could help control blood sugar in type 2 diabetes
NCT ID NCT06354660
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new weekly medicine called retatrutide in 537 adults with type 2 diabetes whose blood sugar was not well controlled by diet and exercise alone. Participants received either the medicine or a placebo for about 11 months. The goal was to see if retatrutide safely lowers blood sugar and helps with weight loss.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Accellacare - Wilmington - 1917 Tradd Court
Wilmington, North Carolina, 28401, United States
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All India Institute of Medical Sciences
Raipur, Chhattisgarh, 492099, India
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All India Institute of Medical Sciences
Bhubaneswar, Odisha, 751019, India
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Ark Clinical Research
Long Beach, California, 90815, United States
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Arké SMO S.A de C.V
Veracruz, 91910, Mexico
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Boeson Research MSO
Missoula, Montana, 59804, United States
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Brij Medical Centre Private Limited
Kanpur, Uttar Pradesh, 208020, India
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Centro de investigación y control metabólico
San Nicolás de los Garza, Nuevo León, 66465, Mexico
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Clinical Research Associates Inc
Nashville, Tennessee, 37203, United States
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Clinical Research Professionals
Chesterfield, Missouri, 63005, United States
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Clinical Research of Central Florida
Winter Haven, Florida, 33880, United States
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Clinical Research of Philadelphia
Philadelphia, Pennsylvania, 19114, United States
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Clínica García Flores SC
Monterrey, Nuevo León, 64610, Mexico
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Consano Clinical Research, LLC
Shavano Park, Texas, 78231, United States
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Cotton O'Neil Clinical Research Center
Topeka, Kansas, 66606, United States
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Delricht Research - Tobias Gadson Boulevard - Charleston
Charleston, South Carolina, 29407, United States
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Dorado Medical Complex
Dorado, 00646, Puerto Rico
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EME RED Hospitalaria
Mérida, Yucatán, 97000, Mexico
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Eastside Research Associates
Redmond, Washington, 98052, United States
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Eternal Heart Care Center and Research Institute
Jaipur, Rajasthan, 302020, India
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Ezy Medical Research
Miami, Florida, 33175, United States
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Government Medical College - Kozhikode
Kozhikode, Kerala, 673008, India
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Grupo Ollin Care
Pachuca, Hidalgo, 42000, Mexico
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Gujarat Endocrin Pvt Ltd
Ahmedabad, Gujarat, 380052, India
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Instituto Jalisciense de Investigacion en Diabetes y Obesidad
Guadalajara, Jalisco, 04460, Mexico
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Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Mexico City, Mexico City, 14080, Mexico
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Lifedoc Research - Lenox Park Drive
Memphis, Tennessee, 38115, United States
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Manassas Clinical Research Center
Manassas, Virginia, 20110, United States
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Medical Care and Research SA de CV
Mérida, Yucatán, 97070, Mexico
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MultiCare Rockwood Cheney Clinic
Cheney, Washington, 99004, United States
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NECCR PrimaCare Research
Fall River, Massachusetts, 02721, United States
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NJ MedCare & NJ Heart
Linden, New Jersey, 07036, United States
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New Horizon Research Center
Miami, Florida, 33165, United States
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Nirmal Hospital Pvt Ltd.
Surat, Gujarat, 395002, India
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Northeast Research Institute (NERI)
Fleming Island, Florida, 32003, United States
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Ponce Medical School Foundation Inc.
Ponce, 00716, Puerto Rico
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Preferred Primary Care Physicians
Uniontown, Pennsylvania, 15401, United States
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Prime Revival Research Institute, LLC
Flower Mound, Texas, 75028, United States
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Providence Health Partners-Center for Clinical Research
Dayton, Ohio, 45439, United States
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San Fernando Valley Health Institute
Canoga Park, California, 91304, United States
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Scottsdale Clinical Trials
Scottsdale, Arizona, 85260, United States
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Texas Valley Clinical Research
Weslaco, Texas, 78596, United States
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Trinity Research Centers
Marietta, Georgia, 30064, United States
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Tucson Clinical Research Institute
Tucson, Arizona, 85712, United States
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Unidad biomedica avanzada monterrey
Monterrey, Nuevo León, 64460, Mexico
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Valley Institute of Research - Fort Worth
Fort Worth, Texas, 76164, United States
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Velocity Clinical Research, Dallas
Dallas, Texas, 75230, United States
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Victoria Hospital, Bangalore Medical College And Research Institute
Bangalore, Karnataka, 560002, India
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Your genes may decide if metformin works for you
- Could a Low-Calorie diet and Weight-Loss drug send type 2 diabetes into remission?
- Could immune cells in fat hold the key to Obesity-Related diseases?
- Your DNA may determine if Weight-Loss drugs work — a trial hunts for clues
- Can a smartphone app and wearable help tame type 2 diabetes?
- Diabetes and antibiotics: a risky mix for the heart?