Your genes may decide if metformin works for you
NCT ID NCT07760883
First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time
Summary
This study is looking at whether a specific genetic variation, called SLC16A11, influences how well the common diabetes drug metformin lowers blood sugar. Adults with type 2 diabetes will be grouped by whether they carry this gene variant and will take extended-release metformin for six months. Researchers will compare changes in HbA1c (a long-term blood sugar measure) and other health markers between the two groups. The goal is to see if genetic information could help personalize diabetes treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Metformin (extended-release)
- What this could lead to
- If successful, this could help doctors tailor metformin treatment based on a person's genetic makeup, improving blood sugar control for those with type 2 diabetes.
- What could go wrong
- This is an observational study, so it cannot prove cause and effect. The results may not apply to all populations, and genetic testing may not be widely available in clinical practice.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
RECRUITINGMexico City, Mexico City, 14080, Mexico
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